Infrared fundus angiography.

Sorsby (I939) used intravenous Kiton green to produce permanent vital staining of the diseased human retina. Other workers have used vital staining dyes in experimental animals. Steinhausen and Loreth (I965) used Lissamin green in investigating the rat retina. Riehm and Podesta (I97 I) used both Patent blue (Disulphine blue) and Lissamin green in an examination of choroidal blood flow in an experimental preparation. They noted that these dyes diffused readily from the choroidal circulation. Amoils and Honey (I969) used Evans blue to produce staining of cryotherapy lesions in the rabbit retina. Kuwamoto (I97I) used acridine orange, a fluorescent dye, to demonstrate retinal blood flow and staining of the poisoned rabbit retina, and Oliver, Zauberman, and Ivry ( I970) used both Disulphine blue and Evans blue for staining retinal lesions. The value of vital staining dyes has been demonstrated by these workers in the experimental animal. but the application of these techniques to the human fundus so far appears unrewarding.